BIO PROJECT-NICOTINE AND HOW DOES IT WORK Nicotine is a hygroscopic oily liquid miscible with piss in its animal form. As a N base it forms solid water soluble salts with acids. Nicotine burns at a temperature below its boiling point and the desiccations puff out at a temperature of 308K despite a low vapour pressure. Because of this virtually of the nicotine is burned when a cig artte is burned. Nicotine is one of the 4000 chemicals prove in the smoke from tobacco plant products. There are many species of tobacco plants..the tabacum species serves as the major(ip) source. Nicotine is absorbed done the skin and the mucosal membranes of the mouth and nose or by the inhalation in the lungs. As nicotine enters the organic structure it is quickly redistributed through blood stream and crosses the blood- sensation barrier ambit the brain within 10-20 seconds of inhalation. The elimination half sustenance of nicotine is nearly 2 hours. Nicotine is metabolized in the liv er by cytochrome P450 enzymes. A major metabolite is cotinine. Glucuronidation and oxidative metabolism of nicotine to cotinine are both suppress by menthol, an additive to mentholated cigarettes thus increasing the half life of nicotine in-vivo. Nicotine discount act as both a stimulant and a sedative.
Immediately after exposure there is a kick caused in part by the drugs stimulation of the suprarenal gland gland glands resulting in the discharge of epinephrine. The rush of adrenaline stimulates the body and causes a sudden bagging of glucose as well as an change magnitude blood pressure, respiration, heart rate. Ni cotine also suppresses the insulin return t! hus resulting in hyperglycemia. In addition nicotine indirectly stimulates the release of docamine in the brain regions that control pleasure and motivation. It is quite same to the other drugs kindred cocaine and heroin. In contrast nicotine can also use a sedative effect, depending on the take of nicotine taken. IN THE substitution NERVOUS SYSTEM- By binding to the nicotinic acetylcholine receptors,...If you pauperism to get a full essay, order it on our website: OrderCustomPaper.com
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