'The effect of Vitamin D supplementation on breast cancer risk\r'

'Abstract \r\nThe have-to doe with of vitamin D postscript on pap pubic louse legal community and diminishment has become a matter of sustained debate. This development proposes to utilize a combination Post-Positivism move up to value the practice. With emerging studies both(prenominal) upholding and decrying the efficacy of Vitamin D in relation to dummy crab louse, thither is a essential pursue this understand in magnitude to enlighten the potential.\r\n Introduction\r\n mamilla crabmeat and vitamin D supplementation have become a substantial military issue of debate as a drive to remark a solution continues. This report card fills a tornado in existing explore by assessing what impact the addition of Vitamin D has on the ginmill and diminishment of face crabmeat.1.1 BackgroundThe efficacy of Vitamin D supplementation in sanctify to prevent or diminish Breast crab louse has become a matter of sustained debate. The Mohr, Gorham and Alcaraz (2012) study presents that there is a direct benefit to the reducing of bosom crab louse by adding Vitamin D both before and after a malignant neoplastic illness diagnosis. Others course credit the impact of Vitamin D on Breast Cancer as only negligible (Prentice, Prettinger and Jackson 2013). unruffled others cite the early stage of research as an obstacle to fully embracing the value of Vitamin D (Yin, Grandi and Raum 2010). Yet, further studies attach Vitamin D and the method of uptake as a pivotal issue (Prentice et al 2013). The goal of this study would be to further see the role of Vitamin D in relation to mammilla pubic louse in women.1.2 Aims and ObjectivesIn this section, the research aims, objectives, and research questions go away be outlined. Firstly, the aim of this research is as follows:\r\nThe following(a) research objectives have been determined:\r\nWhat is the effect of vitamin D supplementation on titty crabmeat riskiness What is the vitamin D status, determ ined by 25-OH vitamin D levels, among women diagnosed with meet cancer 1.3 investigate QuestionsThe research question is:\r\nWhat argon the known associations with Vitamin D supplementation and pectus cancer What argon the key factors that have been impacted by Vitamin D supplementation of cancer Do the authority of Vitamin D ingestion have an impact on effectiveness What is the potential emerging research breeding 2 Literature Re see 2.1 Factors that contrisolelye to Breast CancerDeficiencies in all forms have long been assign with the increasing the probability for cancer of all varieties (Pearce and Cheetham 2010). Factors including the need of Vitamin D have been linked to breast cancer diagnosis in women (Chung, Lee and Terasawa 2011). With lifestyle choices and semipermanent habits playing a pivotal role in a cancer diagnosis, the impact of a virtuoso element is debateable (Brasky, Lampe and Potter 2010). Diseases including Rickets and osteomalacia are now tied to vi tamin D deficiency, making a breast cancer link plausible (Pearce et al 2010). The movement of or lack of vitamins are argued to impact a breast cancer diagnosis.2.2 Vitamin D and Breast Cancer supplementation in WomenA wide array of professionals ranging crosswise clinical finishs, autoimmunity, cardiology and cancer fields agree that the Vitamin D supplementation is a benefit to the effort to accession breast prevention efforts (Souberbielle, Jeanjacques Body and Lappe 2010). Yet, Prentice et al (2013), while maintaining the mode regularise value of the supplementation practice, argue that the reduction in breast cancer situation due to this factor is only suggestive, not conclusive.2.3 Vitamin D and Breast Cancer Prevention OptionWolff and Guiliano (2011) have erect that Vitamin D as a supplement is headmaster to a dietary phthisis of vitamin D. This study charts a correlation among the incidents of breast cancer prevention and the dietary method of vitamin intake. It i s insufficient to rely on any single indicator in as a prevention mechanism (Thacher and Clarke 2011). Further, the benefits of vitamin D are only at the observational stage and cannot be fully accredited (Ibid).2.4TrendsThe combination of Calcium/Vitamin D is providing an avenue for research towards a diminished rate of breast cancer (Bolland, Grey, Gamble and Reid 2011). Conversely, Brunner, Wactawski-Wende and Cann (2011) illustrate that there is no substantial reduction in breast cancer among their studies participants employing this combination.\r\n3. Methodology\r\n The methodology focuses on an translation of the approaches considered:\r\nWhat is the effect of vitamin D supplementation on breast cancer risk What is the vitamin D status, determined by 25-OH vitamin D levels, among women diagnosed with breast cancer3.1 ApproachPositivism, quantitative method, provides solutions abatementing in math, producing experimental info (Yin 2003). Interpretivism or qualitative use s the interpretive approach utilizing instruments like coding. Post-Positivism, a combination of the two is outdo suited to determine the impact of Vitamin D supplementation on breast cancer in women (Bryan and price 2007).\r\nBoth inductive and deductive approaches were considered. Bryan et al (2007) view both approaches as ‘connected’ with distinct elements, but the connection are not fixed. Therefore settled the use of a mixed method or post-positivism method was chosen as the surpass approach.3.2 Research StrategyThis study go away collect and analyse selective information-based data (Biggam 2012). The exercising of both primary and petty(a) research material will provide learning and fundamental clarity to the study (Yin 2003). The empirical research in this study deals with an in-depth review of breast cancer fictional characters, survivors and relevant health check professionals. Primary data will be accumulated through the creation and utilization of a survey directly transmitted to breast cancer survivors and oncological professionals (Ibid). Prior and existing case studies will be evaluated utilizing secondary sources alongside the application of a primary source survey issued to the breast cancer survivors and members of the oncologist community (Yin 2003). This research strategy is best suited to facilitate a well locomote evaluation of issues that promote various perspectives in order to gain a comprehensive understanding of the link between Vitamin D supplementation and breast cancer (Lock, Silvermand and Spirduso 2010).3.4 Data Collection Methods and InstrumentsThe collection methods used in this study were:\r\nPrimary data using Surveys from survivors and medical professionals (Saunders et al 2007). Secondary breast cancer data via journal and peer reviewed article\r\nThe primary disadvantages rest in the limited capacity to check answers or develop further details. Further, obtaining primary data may be very high (Yin 2003).\r\n7. References\r\nBiggam, J. (2012) Succeeding with Your track’s Dissertation. 2nd ed.Berks. McGraw-Hill\r\nBoll, Grey, A., Gamble, G. and Reid, I. 2011. Calcium and vitamin D supplements and health outcomes: a reanalysis of the Women’s Health foremost (WHI) limited-access data set. The American journal of clinical nutrition, 94 (4), pp. 1144â€1149.\r\nBrasky, T., Lampe, J., Potter, J., Patterson, R. and White, E. 2010. forcefulness supplements and breast cancer risk in the VITamins And life-style (VITAL) Cohort. Cancer Epidemiology Biomarkers & Prevention, 19 (7), pp. 1696â€1708.\r\nBrunner, R., Wactawski-Wende, J., Caan, B., Cochrane, B., Chlebowski, R., Gass, M., Jacobs, E., Lacroix, A., Lane, D., Larson, J. and Others. 2011. The effect of calcium positive(p) vitamin D on risk for invasive cancer: results of the Women’s Health Initiative (WHI) calcium irrefutable vitamin D randomized clinical trial. Nutrition and cancer, 63 (6) , pp. 827â€841.\r\nBryan and Bell, (2007)Buisness Research Methods Oxford. University Press\r\nChung, M., Lee, J., Terasawa, T., Lau, J. and Trikalinos, T. 2011. Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the US birth control device Services Task Force. Annals of Internal Medicine, clv (12), pp. 827â€838.\r\nLocke L. F., Silverman S J and Spirduso, W, W (2010, pg 198) Reading and understand Research. 3rd ed.\r\nMohr, S., Gorham, E., Alcaraz, J., Kane, C., Macera, C., Parsons, J., Wingard, D. and Garl. 2012. Does the evidence for an inverse relationship between serum vitamin D status and breast cancer risk satisfy the Hill criteria?. Dermato-endocrinology, 4 (2), pp. 152â€157.\r\nPearce, S., Cheetham, T. and Others. 2010. diagnosis and management of vitamin D deficiency. Bmj, 340 p. 5664.\r\nPrentice, R., Pettinger, M., Jackson, R., Wactawski-Wende, J., Lacroix, A., Anderson, G., Chlebowski, R., Manson, J., Van Horn, L., Vitolins, M. and Others. 2013. Health risks and benefits from calcium and vitamin D supplementation: Women’s Health Initiative clinical trial and cohort study. Osteoporosis International, 24 (2), pp. 567â€580.\r\nSerrano, J., De Lorenzo, D., Cassanye, A., grocery store’In-Gari, M., Espinel, A., Delgado, M., Pamplona, R. and Portero-Otin, M. 2013. Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile.Genes & nutrition, 8 (6), pp. 561â€569.\r\nSouberbielle, J., Body, J., Lappe, J., Plebani, M., Shoenfeld, Y., Wang, T., Bischoff-Ferrari, H., Cavalier, E., Ebeling, P., Fardellone, P. and Others. 2010. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice.Autoimmunity reviews, 9 (11), pp. 709â€715.\r\nThacher, T. and Clarke, B. 2011. Vitamin D insufficiency. 86 (1), pp. 50â€60.\r\nYin, L., Gr, I, N., Raum, E., Haug, U., Arndt, V. and Brenner, H. 2010. Meta-analysis: serum vitamin D and breast cancer risk. European Journal of Cancer, 46 (12), pp. 2196â€2205.\r\nYin, R. 2003. Case study research. Thousand Oaks, Calif.: Sage Publications.Pallant, J. (2010) SPSS\r\n8. Gantt Chart\r\n'